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• 2004

  Epidemiology, transmission dynamics and control of SARS: The 2002-2003 epidemic

  Anderson, R. M., Fraser, C., Ghani, A. C., Donnelly, C. A., Riley, S., Ferguson, N. M., Leung, G. M., Lam, T. H. & Hedley, A. J., Jul 29 2004, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 359, 1447, p. 1091-1105 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  401 Citations (Scopus)

• Establishment and evaluation of a smoking cessation clinic in Hong Kong: A model for the future service provider

  Abdullah, A. S. M., Hedley, A. J., Chan, S. S. C., Ho, W. W. N. & Lam, T. H., Sept 2004, In: Journal of Public Health. 26, 3, p. 239-244 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  43 Citations (Scopus)

• False-positive results in a recombinant Severe Acute Respiratory Syndrome-Associated Coronavirus (SARS-CoV) nucleocapsid enzyme-linked immunosorbent assay due to HCoV-OC43 and HCoV-229E rectified by western blotting with recombinant SARS-CoV spike polypeptide

  Woo, P. C. Y., Lau, S. K. P., Wong, B. H. L., Chan, K. H., Hui, W. T., Kwan, G. S. W., Peiris, J. S. M., Couch, R. B. & Yuen, K. Y., Dec 2004, In: Journal of Clinical Microbiology. 42, 12, p. 5885-5888 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  75 Citations (Scopus)

• For a better, safer and healthier tomorrow - Our commitment to research in emerging infectious diseases at the University of Hong Kong

  Woo, P. C. Y., Wong, S. S. Y., Chan, K. H., Guan, Y., Kao, R. Y. T., Yuen, K. Y., Lau, S. K. P., Peiris, J. S. M., Ho, P. L., Poon, L. L. M., Zheng, B. J. & Yam, W. C., Dec 2004, In: Nature Medicine. 10, 12 SUPPL., p. i

  Research output: Contribution to journal › Short survey › peer-review

• Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia

  Li, K. S., Guan, Y., Wang, J., Smith, G. J. D., Xu, K. M., Duan, L., Rahardjo, A. P., Puthavathana, P., Buranathai, C., Nguyen, T. D., Estoepangestie, A. T. S., Chaisingh, A., Auewarakui, P., Long, H. T., Hanh, N. T. H., Webby, R. J., Poon, L. L. M., Chen, H., Shortridge, K. F. & Yuen, K. Y. & 2 others, Webster, R. G. & Peiris, J. S. M., Jul 8 2004, In: Nature. 430, 6996, p. 209-213 5 p.

  Research output: Contribution to journal › Article › peer-review
  1163 Citations (Scopus)

• H5N1 influenza: A protean pandemic threat

  Guan, Y., Poon, L. L. M., Cheung, C. Y., Ellis, T. M., Lim, W., Lipatov, A. S., Chan, K. H., Sturm-Ramirez, K. M., Cheung, C. L., Leung, Y. H. C., Yuen, K. Y., Webster, R. G. & Peiris, J. S. M., May 21 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 21, p. 8156-8161 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  382 Citations (Scopus)

• Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics

  Kao, R. Y., Tsui, W. H. W., Lee, T. S. W., Tanner, J. A., Watt, R. M., Huang, J. D., Hu, L., Chen, G., Chen, Z., Zhang, L., He, T., Chan, K. H., Tse, H., To, A. P. C., Ng, L. W. Y., Wong, B. C. W., Tsoi, H. W., Yang, D., Ho, D. D. & Yuen, K. Y., Sept 2004, In: Chemistry and Biology. 11, 9, p. 1293-1299 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  153 Citations (Scopus)

• Impact of obesity and body fat distribution on cardiovascular risk factors in Hong Kong Chinese

  Thomas, G. N., Ho, S. Y., Lam, K. S. L., Janus, E. D., Hedley, A. J. & Tai, H. L., 2004, In: Obesity Research. 12, 11, p. 1805-1813 9 p.

  Research output: Contribution to journal › Article › peer-review
  105 Citations (Scopus)

• Initial viral load and the outcomes of SARS

  Chu, C. M., Poon, L. L. M., Cheng, V. C. C., Chan, K. S., Hung, I. F. N., Wong, M. M. L., Chan, K. H., Leung, W. S., Tang, B. S. F., Chan, V. L., Ng, W. L., Sim, T. C., Ng, P. W., Law, K. I., Tse, D. M. W., Peiris, J. S. M. & Yuen, K. Y., Nov 23 2004, In: CMAJ. Canadian Medical Association Journal. 171, 11, p. 1349-1352 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  159 Citations (Scopus)

• In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds

  Chen, F., Chan, K. H., Jiang, Y., Kao, R. Y. T., Lu, H. T., Fan, K. W., Cheng, V. C. C., Tsui, W. H. W., Hung, I. F. N., Lee, T. S. W., Guan, Y., Peiris, J. S. M. & Yuen, K. Y., Sept 2004, In: Journal of Clinical Virology. 31, 1, p. 69-75 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  497 Citations (Scopus)

• Lack of evidence that DNA in antibiotic preparations is a source of antibiotic resistance genes in bacteria from animal or human sources

  Lau, S. K. P., Woo, P. C. Y., To, A. P. C., Lau, A. T. K. & Yuen, K. Y., Aug 2004, In: Antimicrobial Agents and Chemotherapy. 48, 8, p. 3141-3146 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)

• Leisure time physical activity and mortality in Hong Kong: Case-control study of all adult deaths in 1998

  Lam, T. H., Ho, S. Y., Hedley, A. J., Mak, K. H. & Leung, G. M., Jul 2004, In: Annals of Epidemiology. 14, 6, p. 391-398 8 p.

  Research output: Contribution to journal › Article › peer-review
  51 Citations (Scopus)

• Longitudinal profile of immunoglobulin G (IgG), IgM, and IgA antibodies against the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in patients with pneumonia due to the SARS coronavirus

  Woo, P. C. Y., Lau, S. K. P., Wong, B. H. L., Chan, K. H., Chu, C. M., Tsoi, H. W., Huang, Y., Peiris, J. S. M. & Yuen, K. Y., Jul 2004, In: Clinical and Diagnostic Laboratory Immunology. 11, 4, p. 665-668 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  147 Citations (Scopus)

• Lymphocyte surge as a marker for immunorestitution disease due to Pneumocystis in jiroveci HIV-negative immunosuppressed hosts

  Cheng, V. C. C., Hung, I. F. N., Wu, A. K. L., Tang, B. S. F., Chu, C. M. & Yuen, K. Y., Jun 2004, In: European Journal of Clinical Microbiology and Infectious Diseases. 23, 6, p. 512-514 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Citations (Scopus)

• Medical treatment of viral pneumonia including SARS in immunocompetent adult

  Cheng, V. C. C., Tang, B. S. F., Wu, A. K. L., Chu, C. M. & Yuen, K. Y., Nov 2004, In: Journal of Infection. 49, 4, p. 262-273 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  78 Citations (Scopus)

• Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome

  Guan, Y., Peiris, J. S. M., Zheng, B., Poon, L. L. M., Chan, K. H., Zeng, F. Y., Chan, C. W. M., Chan, M. N., Chen, J. D., Chow, K. Y. C., Hon, C. C., Hui, K. H., Li, J., Li, V. Y. Y., Wang, Y., Leung, S. W., Yuen, K. Y. & Leung, F. C., Jan 10 2004, In: Lancet. 363, 9403, p. 99-104 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  121 Citations (Scopus)

• Nucleocapsid protein as early diagnostic marker for SARS

  Che, X. Y., Hao, W., Wang, Y., Di, B., Yin, K., Xu, Y. C., Feng, C. S., Wan, Z. Y., Cheng, V. C. C. & Yuen, K. Y., Nov 2004, In: Emerging Infectious Diseases. 10, 11, p. 1947-1949 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  115 Citations (Scopus)

• Obesity and depressive symptoms in Chinese elderly

  Li, Z. B., Ho, S. Y., Chan, W. M., Ho, K. S., Li, M. P., Leung, G. M. & Lam, T. H., Jan 2004, In: International Journal of Geriatric Psychiatry. 19, 1, p. 68-74 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  137 Citations (Scopus)

• Penicilliosis in China

  Wong, S. S. Y. & Yuen, K. Y., Jul 2004, In: Mycopathologia. 158, 2, p. 147-150 4 p.

  Research output: Contribution to journal › Editorial › peer-review
  8 Citations (Scopus)

• Perceived peer smoking prevalence and its association with smoking behaviours and intentions in Hong Kong Chinese adolescents

  Man, K. L., Sai, Y. H. & Tai, H. L., Sept 2004, In: Addiction. 99, 9, p. 1195-1205 11 p.

  Research output: Contribution to journal › Review article › peer-review
  44 Citations (Scopus)

• Phenotypic and molecular characterization of erythromycin resistance in four isolates of Streptococcus-like gram-positive cocci causing bacteremia

  Woo, P. C. Y., To, A. P. C., Lau, S. K. P., Fung, A. M. Y. & Yuen, K. Y., Jul 2004, In: Journal of Clinical Microbiology. 42, 7, p. 3303-3305 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• Possible Central Nervous System Infection by SARS Coronavirus

  Lau, K. K., Yu, W. C., Chu, C. M., Lau, S. T., Sheng, B. & Yuen, K. Y., Feb 2004, In: Emerging Infectious Diseases. 10, 2, p. 342-344 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  329 Citations (Scopus)

• Potent neutralization antibody elicited in mice by SARS-associated coronavirus spike protein S1 domain

  Zhang, Y., Yang, F., Li, Y. H., Li, W. H., Tu, X. M., Wei, Q., Zhu, H., Liu, L., Wang, H., Qin, C., Yuan, G. Y., He, W. & Wang, S. H., 2004, In: Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology. 18, 3, p. 258-260 3 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Preparation and characterization of monoclonal antibodies against S1 domain at N-terminal residues 249 to 667 of SARS-associated coronavirus S1 protein.

  Wen, K., Mei, Y. B., Qiu, L. W., Liao, Z. Y., Yuen, K. Y. & Che, X. Y., Jan 2004, In: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA. 24, 1, p. 1-6 6 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Prevalence of non-pneumonic infections with SARS-correlated virus [1] (multiple letters)

  Yip, C. W., Hon, C. C., Zeng, F., Chow, K. Y. C., Leung, F. C. C., Theron, M., Zhou, Y. H., Young, M., Woo, P. C. Y., Lau, S. K. P. & Yuen, K. Y., May 29 2004, In: Lancet. 363, 9423, p. 1825-1827 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  6 Citations (Scopus)

• Rapid detection of the Severe Acute Respiratory Syndrome (SARS) coronavirus by a loop-mediated isothermal amplification assay

  Poon, L. L. M., Leung, C. S. W., Tashiro, M., Chan, K. H., Wong, B. W. Y., Yuen, K. Y., Guan, Y. & Peiris, J. S. M., Jun 2004, In: Clinical Chemistry. 50, 6, p. 1050-1052 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  105 Citations (Scopus)

• Re-emergence of fatal human influenza A subtype H5N1 disease

  Peiris, J. S. M., Yu, W. C., Leung, C. W., Cheung, C. Y., Ng, W. F., Nicholls, J. M., Ng, T. K., Chan, K. H., Lai, S. T., Lim, W. L., Yuen, K. Y. & Guan, Y., Feb 21 2004, In: Lancet. 363, 9409, p. 617-619 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  721 Citations (Scopus)

• Relative rates of non-pneumonic SARS coronavirus infection and SARS coronavirus pneumonia

  Woo, P. C. Y., Lau, S. K. P., Tsoi, H. W., Chan, K. H., Wong, B. H. L., Che, X. Y., Tam, V. K. P., Tam, S. C. F., Cheng, V. C. C., Hung, I. F. N., Wong, S. S. Y., Zheng, B. J., Guan, Y. & Yuen, K. Y., Mar 13 2004, In: Lancet. 363, 9412, p. 841-845 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  125 Citations (Scopus)

• Reverse Transcriptase PCR Diagnostic Assay for the Coronavirus Associated with Severe Acute Respiratory Syndrome

  Hui, R. K. H., Zeng, F., Chan, C. M. N., Yuen, K. Y., Peiris, J. S. M. & Leung, F. C. C., May 2004, In: Journal of Clinical Microbiology. 42, 5, p. 1994-1999 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  40 Citations (Scopus)

• Role of lopinavir/ritonavir in the treatment of SARS: Initial virological and clinical findings

  Chu, C. M., Cheng, V. C. C., Hung, I. F. N., Wong, M. M. L., Chan, K. H., Chan, K. S., Kao, R. Y. T., Poon, L. L. M., Wong, C. L. P., Guan, Y., Peiris, J. S. M. & Yuen, K. Y., Mar 2004, In: Thorax. 59, 3, p. 252-256 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1365 Citations (Scopus)

• SARS: Market, toilet, hospital, and laboratory

  Yuen, K. Y., Jun 2004, In: Hong Kong Medical Journal. 10, 3, p. 148-149 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• SARS-CoV antibody prevalence in all Hong Kong patient contacts

  Leung, G. M., Chung, P. H., Tsang, T., Lim, W., Chan, S. K. K., Chau, P., Donnelly, C. A., Ghani, A. C., Fraser, C., Riley, S., Ferguson, N. M., Anderson, R. M., Law, Y. L., Mok, T., Ng, T., Fu, A., Leung, P. Y., Peiris, J. S. M., Lam, T. H. & Hedley, A. J., Sept 2004, In: Emerging Infectious Diseases. 10, 9, p. 1653-1656 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  70 Citations (Scopus)

• Secondhand smoke exposure, smoking hygiene, and hospitalization in the first 18 months of life

  Leung, G. M., Ho, L. M. & Lam, T. H., Jul 2004, In: Archives of Pediatrics and Adolescent Medicine. 158, 7, p. 687-693 7 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Sensitive and specific monoclonal antibody-based capture enzyme immunoassay for detection of nucleocapsid antigen in sera from patients with severe acute respiratory syndrome

  Che, X. Y., Qiu, L. W., Pan, Y. X., Wen, K., Hao, W., Zhang, L. Y., Wang, Y. D., Liao, Z. Y., Hua, X., Cheng, V. C. C. & Yuen, K. Y., Jun 2004, In: Journal of Clinical Microbiology. 42, 6, p. 2629-2635 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  119 Citations (Scopus)

• Severe acute respiratory syndrome: Report of treatment and outcome after a major outbreak

  Sung, J. J. Y., Wu, A., Joynt, G. M., Yuen, K. Y., Lee, N., Chan, P. K. S., Cockram, C. S., Ahuja, A. T., Yu, L. M., Wong, V. W. & Hui, D. S. C., May 2004, In: Thorax. 59, 5, p. 414-420 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  165 Citations (Scopus)

• Severe acute respiratory syndrome

  Peiris, J. S. M., Guan, Y. & Yuen, K. Y., Dec 2004, In: Nature Medicine. 10, 12S, p. S88-S97

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  872 Citations (Scopus)

• Smoking, drinking and colorectal cancer in Hong Kong Chinese: A case-control study

  Ho, J. W. C., Lam, T. H., Tse, C. W., Chiu, L. K. M., Lam, H. S., Leung, P. F., Ng, K. C., Ho, S. Y., Woo, J., Leung, S. S. F. & Yuen, S. T., Apr 20 2004, In: International Journal of Cancer. 109, 4, p. 587-597 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  38 Citations (Scopus)

• Smoking and depressive symptoms in Chinese elderly in Hong Kong

  Lam, T. H., Li, Z. B., Ho, S. Y., Chan, W. M., Ho, K. S., Li, M. P. & Leung, G. M., Sept 2004, In: Acta Psychiatrica Scandinavica. 110, 3, p. 195-200 6 p.

  Research output: Contribution to journal › Article › peer-review
  46 Citations (SciVal)

• Smoking and tuberculosis among the elderly in Hong Kong

  Leung, C. C., Li, T., Lam, T. H., Yew, W. W., Law, W. S., Tam, C. M., Chan, W. M., Chan, C. K., Ho, K. S. & Chang, K. C., Nov 1 2004, In: American Journal of Respiratory and Critical Care Medicine. 170, 9, p. 1027-1033 7 p.

  Research output: Contribution to journal › Article › peer-review
  137 Citations (Scopus)

• Smoking increases the risk of death from tuberculosis four-fold in adult males in India

  Gajalakshmi, V., Peto, R., Kanaka, T. S., Jha, P., Yach, D., Raviglione, M. C., Lam, T. H. & Leung, G. M., 2004, In: Evidence-Based Healthcare. 8, 1, p. 27-29 3 p.

  Research output: Contribution to journal › Short survey › peer-review

• Spontaneous pneumomediastinum in patients with severe acute respiratory syndrome

  Chu, C. M., Leung, Y. Y., Hui, J. Y. H., Hung, I. F. N., Chan, V. L., Leung, W. S., Law, W. S., Chan, C. S., Chan, K. S. & Yuen, K. Y., Jun 2004, In: European Respiratory Journal. 23, 6, p. 802-804 3 p.

  Research output: Contribution to journal › Article › peer-review
  112 Citations (Scopus)

• Stage of change for general health promotion action and health-related lifestyle practices in Chinese adults

  Lam, T. H., Chan, B., Ho, S. Y. & Chan, W. M., Mar 2004, In: Preventive Medicine. 38, 3, p. 302-308 7 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• "Streptococcus milleri" endocarditis caused by Streptococcus anginosus

  Woo, P. C. Y., Tse, H., Chan, K. M., Lau, S. K. P., Fung, A. M. Y., Yip, K. T., Tam, D. M. W., Ng, K. H. L., Que, T. L. & Yuen, K. Y., Feb 2004, In: Diagnostic Microbiology and Infectious Disease. 48, 2, p. 81-88 8 p.

  Research output: Contribution to journal › Article › peer-review
  60 Citations (Scopus)

• Streptococcus sinensis may react with Lancefield group F antiserum

  Woo, P. C. Y., Teng, J. L. L., Leung, K. W., Lau, S. K. P., Tse, H., Wong, B. H. L. & Yuen, K. Y., Nov 2004, In: Journal of Medical Microbiology. 53, 11, p. 1083-1088 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  29 Citations (Scopus)

• Subjective health and fibrinogen in a healthy Chinese cohort

  Fielding, R., Lam, T. H., Ho, S. Y. & Janus, E. D., Nov 2004, In: British Journal of Health Psychology. 9, 4, p. 523-532 10 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Suicidality among high school students in Hong Kong, SAR

  Yip, P. S. F., Liu, K. Y., Lam, T. H., Stewart, S. M., Chen, E. & Fan, S., Sept 2004, In: Suicide and Life-Threatening Behavior. 34, 3, p. 284-297 14 p.

  Research output: Contribution to journal › Article › peer-review
  47 Citations (Scopus)

• Suicidality and cultural values among Hong Kong adolescents

  Lam, T. H., Stewart, S. M., Yip, P. S. F., Leung, G. M., Ho, L. M., Ho, S. Y. & Lee, P. W. H., Feb 2004, In: Social Science and Medicine. 58, 3, p. 487-498 12 p.

  Research output: Contribution to journal › Article › peer-review
  47 Citations (Scopus)

• The aetiology, origins, and diagnosis of severe acute respiratory syndrome

  Poon, L. L. M., Guan, Y., Nicholls, J. M., Yuen, K. Y. & Peiris, J. S. M., Nov 1 2004, In: Lancet Infectious Diseases. 4, 11, p. 663-671 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  148 Citations (Scopus)

• The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: An analysis of all 1755 patients

  Leung, G. M., Medley, A. J., Ho, L. M., Chau, P., Wong, I. O. L., Thach, T. Q., Ghani, A. C., Donnelly, C. A., Fraser, C., Riley, S., Ferguson, N. M., Anderson, R. M., Tsang, T., Leung, P. Y., Wong, V., Chan, J. C. K., Tsui, E., Lo, S. V. & Lam, T. H., Nov 2 2004, In: Annals of Internal Medicine. 141, 9, p. 662-673 12 p.

  Research output: Contribution to journal › Article › peer-review
  293 Citations (Scopus)

• The public health viewpoint

  Leung, G. M., Hedley, A. J., Lau, E. M. C. & Lam, T. H., 2004, At the Epicentre: Hong Kong and the SARS outbreak. Hong Kong University Press, HKU, p. 55-80 26 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  6 Citations (Scopus)