Nucleocapsid protein as early diagnostic marker for SARS

Xiao Yan Che; Wei Hao; Yadi Wang; Biao Di; Kai Yin; Yin Chao Xu; Chang Sen Feng; Zhuo Yue Wan; Vincent C.C. Cheng; Kwok Yung Yuen

doi:10.3201/eid1011.040516

Nucleocapsid protein as early diagnostic marker for SARS

Xiao Yan Che, Wei Hao, Yadi Wang, Biao Di, Kai Yin, Yin Chao Xu, Chang Sen Feng, Zhuo Yue Wan, Vincent C.C. Cheng, Kwok Yung Yuen

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115 Citations (Scopus)

Abstract

Serum samples from 317 patients with severe acute respiratory syndrome (SARS) were tested for the nucleocapsid (N) protein of SARS-associated coronavirus, with sensitivities of 94% and 78% for the first 5 days and 6-10 days after onset, respectively. The specificity was 99.9%. N protein can be used as an early diagnostic maker for SARS.

Original language	English
Pages (from-to)	1947-1949
Number of pages	3
Journal	Emerging Infectious Diseases
Volume	10
Issue number	11
DOIs	https://doi.org/10.3201/eid1011.040516
Publication status	Published - Nov 2004
Externally published	Yes

ASJC Scopus Subject Areas

Epidemiology
Microbiology (medical)
Infectious Diseases

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Cite this

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abstract = "Serum samples from 317 patients with severe acute respiratory syndrome (SARS) were tested for the nucleocapsid (N) protein of SARS-associated coronavirus, with sensitivities of 94% and 78% for the first 5 days and 6-10 days after onset, respectively. The specificity was 99.9%. N protein can be used as an early diagnostic maker for SARS.",

author = "Che, {Xiao Yan} and Wei Hao and Yadi Wang and Biao Di and Kai Yin and Xu, {Yin Chao} and Feng, {Chang Sen} and Wan, {Zhuo Yue} and Cheng, {Vincent C.C.} and Yuen, {Kwok Yung}",

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AU - Che, Xiao Yan

AU - Hao, Wei

AU - Wang, Yadi

AU - Di, Biao

AU - Yin, Kai

AU - Xu, Yin Chao

AU - Feng, Chang Sen

AU - Wan, Zhuo Yue

AU - Cheng, Vincent C.C.

AU - Yuen, Kwok Yung

PY - 2004/11

Y1 - 2004/11

N2 - Serum samples from 317 patients with severe acute respiratory syndrome (SARS) were tested for the nucleocapsid (N) protein of SARS-associated coronavirus, with sensitivities of 94% and 78% for the first 5 days and 6-10 days after onset, respectively. The specificity was 99.9%. N protein can be used as an early diagnostic maker for SARS.

AB - Serum samples from 317 patients with severe acute respiratory syndrome (SARS) were tested for the nucleocapsid (N) protein of SARS-associated coronavirus, with sensitivities of 94% and 78% for the first 5 days and 6-10 days after onset, respectively. The specificity was 99.9%. N protein can be used as an early diagnostic maker for SARS.

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JF - Emerging Infectious Diseases

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Nucleocapsid protein as early diagnostic marker for SARS

Abstract

ASJC Scopus Subject Areas

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