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2004
Coronavirus infection in an AIDS patient [1]
Wong, A. T. Y., Tsang, O. T. Y., Wong, K. H., Wong, M. Y. F., Lim, W. L., Zheng, B. J., Lee, S. S., Lai, S. T., Yuen, K. Y., Choi, K. W., Tso, E. Y. K., Chau, T. N., Tong, W. L., Chiu, M. C. & Yu, W. C., Mar 26 2004, In: AIDS. 18, 5, p. 829-830 2 p.Research output: Contribution to journal › Letter › peer-review
22 Citations (Scopus) -
Depressive symptoms among Hong Kong adolescents: Relation to atypical sexual feelings and behaviors, gender dissatisfaction, pubertal timing, and family and peer relationships
Lam, T. H., Stewart, S. M., Leung, G. M., Lee, P. W. H., Wong, J. P. S. & Ho, L. M., Oct 2004, In: Archives of Sexual Behavior. 33, 5, p. 487-496 10 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
Detection of SARS Coronavirus in Patients with Severe Acute Respiratory Syndrome by Conventional and Real-Time Quantitative Reverse Transcription-PCR Assays
Poon, L. L. M., Chan, K. H., Wong, O. K., Cheung, T. K. W., Ng, I., Zheng, B., Seto, W. H., Yuen, K. Y., Guan, Y. & Peiris, J. S. M., Jan 2004, In: Clinical Chemistry. 50, 1, p. 67-72 6 p.Research output: Contribution to journal › Article › peer-review
Open Access110 Citations (Scopus) -
Detection of SARS Coronavirus in Patients with Suspected SARS
Chan, K. H., Poon, L. L. L. M., Cheng, V. C. C., Guan, Y., Hung, I. F. N., Kong, J., Yam, L. Y. C., Seto, W. H., Yuen, K. Y. & Peiris, J. S. M., Feb 2004, In: Emerging Infectious Diseases. 10, 2, p. 294-299 6 p.Research output: Contribution to journal › Article › peer-review
Open Access266 Citations (Scopus) -
Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in SARS patients by enzyme-linked immunosorbent assay
Lau, S. K. P., Woo, P. C. Y., Wong, B. H. L., Tsoi, H. W., Woo, G. K. S., Poon, R. W. S., Chan, K. H., Wei, W. I., Malik Peiris, J. S. & Yuen, K. Y., Jul 2004, In: Journal of Clinical Microbiology. 42, 7, p. 2884-2889 6 p.Research output: Contribution to journal › Article › peer-review
Open Access107 Citations (Scopus) -
Detection of Specific Antibodies to Severe Acute Respiratory Syndrome (SARS) Coronavirus Nucleocapsid Protein for Serodiagnosis of SARS Coronavirus Pneumonia
Woo, P. C. Y., Lau, S. K. P., Wong, B. H. L., Tsoi, H. W., Fung, A. M. Y., Chan, K. H., Tam, V. K. P., Peiris, J. S. M. & Yuen, K. Y., May 2004, In: Journal of Clinical Microbiology. 42, 5, p. 2306-2309 4 p.Research output: Contribution to journal › Article › peer-review
Open Access113 Citations (Scopus) -
Direct detection of Mycobacterium tuberculosis in clinical specimens using single-tube biotinylated nested polymerase chain reaction-enzyme linked immunoassay (PCR-ELISA)
Yam, W. C., Cheng, V. C. C., Hui, W. T., Wang, L. N., Seto, W. H. & Yuen, K. Y., Apr 2004, In: Diagnostic Microbiology and Infectious Disease. 48, 4, p. 271-275 5 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
Direct detection of rifampin-resistant Mycobacterium tuberculosis in respiratory specimens by PCR-DNA sequencing
Yam, W. C., Tam, C. M., Leung, C. C., Tong, H. L., Chan, K. H., Leung, E. T. Y., Wong, K. C., Yew, W. W., Seto, W. H., Yuen, K. Y. & Ho, P. L., Oct 2004, In: Journal of Clinical Microbiology. 42, 10, p. 4438-4443 6 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Citations (Scopus) -
Effects of single nucleotide polymorphisms in the RANTES promoter region in healthy and HIV-infected indigenous Chinese
Zhao, X. Y., Lee, S. S., Wong, K. H., Chan, K. C. W., Ma, S., Yam, W. C., Yuen, K. Y., Ng, M. H. & Zheng, B. J., Aug 2004, In: European Journal of Immunogenetics. 31, 4, p. 179-183 5 p.Research output: Contribution to journal › Article › peer-review
27 Citations (Scopus) -
Eggerthella hongkongensis sp. nov. and eggerthella sinensis sp. nov., two novel Eggerthella species, account for half of the cases of Eggerthella bacteremia
Lau, S. K. P., Woo, P. C. Y., Woo, G. K. S., Fung, A. M. Y., Wong, M. K. M., Chan, K. M., Tam, D. M. W. & Yuen, K. Y., Aug 2004, In: Diagnostic Microbiology and Infectious Disease. 49, 4, p. 255-263 9 p.Research output: Contribution to journal › Article › peer-review
106 Citations (Scopus) -
Enterococcus cecorum Empyema Thoracis Successfully Treated with Cefotaxime
Woo, P. C. Y., Tam, D. M. W., Lau, S. K. P., Fung, A. M. Y. & Yuen, K. Y., Feb 2004, In: Journal of Clinical Microbiology. 42, 2, p. 919-922 4 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Citations (Scopus) -
Epidemiology, transmission dynamics and control of SARS: The 2002-2003 epidemic
Anderson, R. M., Fraser, C., Ghani, A. C., Donnelly, C. A., Riley, S., Ferguson, N. M., Leung, G. M., Lam, T. H. & Hedley, A. J., Jul 29 2004, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 359, 1447, p. 1091-1105 15 p.Research output: Contribution to journal › Article › peer-review
Open Access401 Citations (Scopus) -
Establishment and evaluation of a smoking cessation clinic in Hong Kong: A model for the future service provider
Abdullah, A. S. M., Hedley, A. J., Chan, S. S. C., Ho, W. W. N. & Lam, T. H., Sept 2004, In: Journal of Public Health. 26, 3, p. 239-244 6 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Citations (Scopus) -
False-positive results in a recombinant Severe Acute Respiratory Syndrome-Associated Coronavirus (SARS-CoV) nucleocapsid enzyme-linked immunosorbent assay due to HCoV-OC43 and HCoV-229E rectified by western blotting with recombinant SARS-CoV spike polypeptide
Woo, P. C. Y., Lau, S. K. P., Wong, B. H. L., Chan, K. H., Hui, W. T., Kwan, G. S. W., Peiris, J. S. M., Couch, R. B. & Yuen, K. Y., Dec 2004, In: Journal of Clinical Microbiology. 42, 12, p. 5885-5888 4 p.Research output: Contribution to journal › Article › peer-review
Open Access75 Citations (Scopus) -
For a better, safer and healthier tomorrow - Our commitment to research in emerging infectious diseases at the University of Hong Kong
Woo, P. C. Y., Wong, S. S. Y., Chan, K. H., Guan, Y., Kao, R. Y. T., Yuen, K. Y., Lau, S. K. P., Peiris, J. S. M., Ho, P. L., Poon, L. L. M., Zheng, B. J. & Yam, W. C., Dec 2004, In: Nature Medicine. 10, 12 SUPPL., p. iResearch output: Contribution to journal › Short survey › peer-review
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Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia
Li, K. S., Guan, Y., Wang, J., Smith, G. J. D., Xu, K. M., Duan, L., Rahardjo, A. P., Puthavathana, P., Buranathai, C., Nguyen, T. D., Estoepangestie, A. T. S., Chaisingh, A., Auewarakui, P., Long, H. T., Hanh, N. T. H., Webby, R. J., Poon, L. L. M., Chen, H., Shortridge, K. F. & Yuen, K. Y. & 2 others, , Jul 8 2004, In: Nature. 430, 6996, p. 209-213 5 p.Research output: Contribution to journal › Article › peer-review
1163 Citations (Scopus) -
H5N1 influenza: A protean pandemic threat
Guan, Y., Poon, L. L. M., Cheung, C. Y., Ellis, T. M., Lim, W., Lipatov, A. S., Chan, K. H., Sturm-Ramirez, K. M., Cheung, C. L., Leung, Y. H. C., Yuen, K. Y., Webster, R. G. & Peiris, J. S. M., May 21 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 21, p. 8156-8161 6 p.Research output: Contribution to journal › Article › peer-review
Open Access382 Citations (Scopus) -
Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics
Kao, R. Y., Tsui, W. H. W., Lee, T. S. W., Tanner, J. A., Watt, R. M., Huang, J. D., Hu, L., Chen, G., Chen, Z., Zhang, L., He, T., Chan, K. H., Tse, H., To, A. P. C., Ng, L. W. Y., Wong, B. C. W., Tsoi, H. W., Yang, D., Ho, D. D. & Yuen, K. Y., Sept 2004, In: Chemistry and Biology. 11, 9, p. 1293-1299 7 p.Research output: Contribution to journal › Article › peer-review
Open Access153 Citations (Scopus) -
Impact of obesity and body fat distribution on cardiovascular risk factors in Hong Kong Chinese
Thomas, G. N., Ho, S. Y., Lam, K. S. L., Janus, E. D., Hedley, A. J. & Tai, H. L., 2004, In: Obesity Research. 12, 11, p. 1805-1813 9 p.Research output: Contribution to journal › Article › peer-review
105 Citations (Scopus) -
Initial viral load and the outcomes of SARS
Chu, C. M., Poon, L. L. M., Cheng, V. C. C., Chan, K. S., Hung, I. F. N., Wong, M. M. L., Chan, K. H., Leung, W. S., Tang, B. S. F., Chan, V. L., Ng, W. L., Sim, T. C., Ng, P. W., Law, K. I., Tse, D. M. W., Peiris, J. S. M. & Yuen, K. Y., Nov 23 2004, In: CMAJ. Canadian Medical Association Journal. 171, 11, p. 1349-1352 4 p.Research output: Contribution to journal › Article › peer-review
Open Access159 Citations (Scopus) -
In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds
Chen, F., Chan, K. H., Jiang, Y., Kao, R. Y. T., Lu, H. T., Fan, K. W., Cheng, V. C. C., Tsui, W. H. W., Hung, I. F. N., Lee, T. S. W., Guan, Y., Peiris, J. S. M. & Yuen, K. Y., Sept 2004, In: Journal of Clinical Virology. 31, 1, p. 69-75 7 p.Research output: Contribution to journal › Article › peer-review
Open Access497 Citations (Scopus) -
Lack of evidence that DNA in antibiotic preparations is a source of antibiotic resistance genes in bacteria from animal or human sources
Lau, S. K. P., Woo, P. C. Y., To, A. P. C., Lau, A. T. K. & Yuen, K. Y., Aug 2004, In: Antimicrobial Agents and Chemotherapy. 48, 8, p. 3141-3146 6 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
Leisure time physical activity and mortality in Hong Kong: Case-control study of all adult deaths in 1998
Lam, T. H., Ho, S. Y., Hedley, A. J., Mak, K. H. & Leung, G. M., Jul 2004, In: Annals of Epidemiology. 14, 6, p. 391-398 8 p.Research output: Contribution to journal › Article › peer-review
51 Citations (Scopus) -
Longitudinal profile of immunoglobulin G (IgG), IgM, and IgA antibodies against the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in patients with pneumonia due to the SARS coronavirus
Woo, P. C. Y., Lau, S. K. P., Wong, B. H. L., Chan, K. H., Chu, C. M., Tsoi, H. W., Huang, Y., Peiris, J. S. M. & Yuen, K. Y., Jul 2004, In: Clinical and Diagnostic Laboratory Immunology. 11, 4, p. 665-668 4 p.Research output: Contribution to journal › Article › peer-review
Open Access147 Citations (Scopus) -
Lymphocyte surge as a marker for immunorestitution disease due to Pneumocystis in jiroveci HIV-negative immunosuppressed hosts
Cheng, V. C. C., Hung, I. F. N., Wu, A. K. L., Tang, B. S. F., Chu, C. M. & Yuen, K. Y., Jun 2004, In: European Journal of Clinical Microbiology and Infectious Diseases. 23, 6, p. 512-514 3 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Citations (Scopus) -
Medical treatment of viral pneumonia including SARS in immunocompetent adult
Cheng, V. C. C., Tang, B. S. F., Wu, A. K. L., Chu, C. M. & Yuen, K. Y., Nov 2004, In: Journal of Infection. 49, 4, p. 262-273 12 p.Research output: Contribution to journal › Article › peer-review
Open Access78 Citations (Scopus) -
Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome
Guan, Y., Peiris, J. S. M., Zheng, B., Poon, L. L. M., Chan, K. H., Zeng, F. Y., Chan, C. W. M., Chan, M. N., Chen, J. D., Chow, K. Y. C., Hon, C. C., Hui, K. H., Li, J., Li, V. Y. Y., Wang, Y., Leung, S. W., Yuen, K. Y. & Leung, F. C., Jan 10 2004, In: Lancet. 363, 9403, p. 99-104 6 p.Research output: Contribution to journal › Article › peer-review
Open Access121 Citations (Scopus) -
Nucleocapsid protein as early diagnostic marker for SARS
Che, X. Y., Hao, W., Wang, Y., Di, B., Yin, K., Xu, Y. C., Feng, C. S., Wan, Z. Y., Cheng, V. C. C. & Yuen, K. Y., Nov 2004, In: Emerging Infectious Diseases. 10, 11, p. 1947-1949 3 p.Research output: Contribution to journal › Article › peer-review
Open Access115 Citations (Scopus) -
Obesity and depressive symptoms in Chinese elderly
Li, Z. B., Ho, S. Y., Chan, W. M., Ho, K. S., Li, M. P., Leung, G. M. & Lam, T. H., Jan 2004, In: International Journal of Geriatric Psychiatry. 19, 1, p. 68-74 7 p.Research output: Contribution to journal › Article › peer-review
Open Access137 Citations (Scopus) -
Penicilliosis in China
Wong, S. S. Y. & Yuen, K. Y., Jul 2004, In: Mycopathologia. 158, 2, p. 147-150 4 p.Research output: Contribution to journal › Editorial › peer-review
8 Citations (Scopus) -
Perceived peer smoking prevalence and its association with smoking behaviours and intentions in Hong Kong Chinese adolescents
Man, K. L., Sai, Y. H. & Tai, H. L., Sept 2004, In: Addiction. 99, 9, p. 1195-1205 11 p.Research output: Contribution to journal › Review article › peer-review
44 Citations (Scopus) -
Phenotypic and molecular characterization of erythromycin resistance in four isolates of Streptococcus-like gram-positive cocci causing bacteremia
Woo, P. C. Y., To, A. P. C., Lau, S. K. P., Fung, A. M. Y. & Yuen, K. Y., Jul 2004, In: Journal of Clinical Microbiology. 42, 7, p. 3303-3305 3 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Possible Central Nervous System Infection by SARS Coronavirus
Lau, K. K., Yu, W. C., Chu, C. M., Lau, S. T., Sheng, B. & Yuen, K. Y., Feb 2004, In: Emerging Infectious Diseases. 10, 2, p. 342-344 3 p.Research output: Contribution to journal › Article › peer-review
Open Access329 Citations (Scopus) -
Potent neutralization antibody elicited in mice by SARS-associated coronavirus spike protein S1 domain
Zhang, Y., Yang, F., Li, Y. H., Li, W. H., Tu, X. M., Wei, Q., Zhu, H., Liu, L., Wang, H., Qin, C., Yuan, G. Y., He, W. & Wang, S. H., 2004, In: Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology. 18, 3, p. 258-260 3 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Preparation and characterization of monoclonal antibodies against S1 domain at N-terminal residues 249 to 667 of SARS-associated coronavirus S1 protein.
Wen, K., Mei, Y. B., Qiu, L. W., Liao, Z. Y., Yuen, K. Y. & Che, X. Y., Jan 2004, In: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA. 24, 1, p. 1-6 6 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
Prevalence of non-pneumonic infections with SARS-correlated virus [1] (multiple letters)
Yip, C. W., Hon, C. C., Zeng, F., Chow, K. Y. C., Leung, F. C. C., Theron, M., Zhou, Y. H., Young, M., Woo, P. C. Y., Lau, S. K. P. & Yuen, K. Y., May 29 2004, In: Lancet. 363, 9423, p. 1825-1827 3 p.Research output: Contribution to journal › Letter › peer-review
Open Access6 Citations (Scopus) -
Rapid detection of the Severe Acute Respiratory Syndrome (SARS) coronavirus by a loop-mediated isothermal amplification assay
Poon, L. L. M., Leung, C. S. W., Tashiro, M., Chan, K. H., Wong, B. W. Y., Yuen, K. Y., Guan, Y. & Peiris, J. S. M., Jun 2004, In: Clinical Chemistry. 50, 6, p. 1050-1052 3 p.Research output: Contribution to journal › Article › peer-review
Open Access105 Citations (Scopus) -
Re-emergence of fatal human influenza A subtype H5N1 disease
Peiris, J. S. M., Yu, W. C., Leung, C. W., Cheung, C. Y., Ng, W. F., Nicholls, J. M., Ng, T. K., Chan, K. H., Lai, S. T., Lim, W. L., Yuen, K. Y. & Guan, Y., Feb 21 2004, In: Lancet. 363, 9409, p. 617-619 3 p.Research output: Contribution to journal › Article › peer-review
Open Access721 Citations (Scopus) -
Relative rates of non-pneumonic SARS coronavirus infection and SARS coronavirus pneumonia
Woo, P. C. Y., Lau, S. K. P., Tsoi, H. W., Chan, K. H., Wong, B. H. L., Che, X. Y., Tam, V. K. P., Tam, S. C. F., Cheng, V. C. C., Hung, I. F. N., Wong, S. S. Y., Zheng, B. J., Guan, Y. & Yuen, K. Y., Mar 13 2004, In: Lancet. 363, 9412, p. 841-845 5 p.Research output: Contribution to journal › Article › peer-review
Open Access125 Citations (Scopus) -
Reverse Transcriptase PCR Diagnostic Assay for the Coronavirus Associated with Severe Acute Respiratory Syndrome
Hui, R. K. H., Zeng, F., Chan, C. M. N., Yuen, K. Y., Peiris, J. S. M. & Leung, F. C. C., May 2004, In: Journal of Clinical Microbiology. 42, 5, p. 1994-1999 6 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Citations (Scopus) -
Role of lopinavir/ritonavir in the treatment of SARS: Initial virological and clinical findings
Chu, C. M., Cheng, V. C. C., Hung, I. F. N., Wong, M. M. L., Chan, K. H., Chan, K. S., Kao, R. Y. T., Poon, L. L. M., Wong, C. L. P., Guan, Y., Peiris, J. S. M. & Yuen, K. Y., Mar 2004, In: Thorax. 59, 3, p. 252-256 5 p.Research output: Contribution to journal › Article › peer-review
Open Access1365 Citations (Scopus) -
SARS: Market, toilet, hospital, and laboratory
Yuen, K. Y., Jun 2004, In: Hong Kong Medical Journal. 10, 3, p. 148-149 2 p.Research output: Contribution to journal › Editorial › peer-review
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SARS-CoV antibody prevalence in all Hong Kong patient contacts
Leung, G. M., Chung, P. H., Tsang, T., Lim, W., Chan, S. K. K., Chau, P., Donnelly, C. A., Ghani, A. C., Fraser, C., Riley, S., Ferguson, N. M., Anderson, R. M., Law, Y. L., Mok, T., Ng, T., Fu, A., Leung, P. Y., Peiris, J. S. M., Lam, T. H. & Hedley, A. J., Sept 2004, In: Emerging Infectious Diseases. 10, 9, p. 1653-1656 4 p.Research output: Contribution to journal › Article › peer-review
Open Access70 Citations (Scopus) -
Secondhand smoke exposure, smoking hygiene, and hospitalization in the first 18 months of life
Leung, G. M., Ho, L. M. & Lam, T. H., Jul 2004, In: Archives of Pediatrics and Adolescent Medicine. 158, 7, p. 687-693 7 p.Research output: Contribution to journal › Article › peer-review
40 Citations (Scopus) -
Sensitive and specific monoclonal antibody-based capture enzyme immunoassay for detection of nucleocapsid antigen in sera from patients with severe acute respiratory syndrome
Che, X. Y., Qiu, L. W., Pan, Y. X., Wen, K., Hao, W., Zhang, L. Y., Wang, Y. D., Liao, Z. Y., Hua, X., Cheng, V. C. C. & Yuen, K. Y., Jun 2004, In: Journal of Clinical Microbiology. 42, 6, p. 2629-2635 7 p.Research output: Contribution to journal › Article › peer-review
Open Access119 Citations (Scopus) -
Severe acute respiratory syndrome: Report of treatment and outcome after a major outbreak
Sung, J. J. Y., Wu, A., Joynt, G. M., Yuen, K. Y., Lee, N., Chan, P. K. S., Cockram, C. S., Ahuja, A. T., Yu, L. M., Wong, V. W. & Hui, D. S. C., May 2004, In: Thorax. 59, 5, p. 414-420 7 p.Research output: Contribution to journal › Article › peer-review
Open Access165 Citations (Scopus) -
Severe acute respiratory syndrome
Peiris, J. S. M., Guan, Y. & Yuen, K. Y., Dec 2004, In: Nature Medicine. 10, 12S, p. S88-S97Research output: Contribution to journal › Review article › peer-review
Open Access872 Citations (Scopus) -
Smoking, drinking and colorectal cancer in Hong Kong Chinese: A case-control study
Ho, J. W. C., Lam, T. H., Tse, C. W., Chiu, L. K. M., Lam, H. S., Leung, P. F., Ng, K. C., Ho, S. Y., Woo, J., Leung, S. S. F. & Yuen, S. T., Apr 20 2004, In: International Journal of Cancer. 109, 4, p. 587-597 11 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Citations (Scopus) -
Smoking and depressive symptoms in Chinese elderly in Hong Kong
Lam, T. H., Li, Z. B., Ho, S. Y., Chan, W. M., Ho, K. S., Li, M. P. & Leung, G. M., Sept 2004, In: Acta Psychiatrica Scandinavica. 110, 3, p. 195-200 6 p.Research output: Contribution to journal › Article › peer-review
46 Citations (SciVal) -
Smoking and tuberculosis among the elderly in Hong Kong
Leung, C. C., Li, T., Lam, T. H., Yew, W. W., Law, W. S., Tam, C. M., Chan, W. M., Chan, C. K., Ho, K. S. & Chang, K. C., Nov 1 2004, In: American Journal of Respiratory and Critical Care Medicine. 170, 9, p. 1027-1033 7 p.Research output: Contribution to journal › Article › peer-review
137 Citations (Scopus)