TY - JOUR
T1 - The use of multi-pronged screening strategy to understand the epidemiology of carbapenemase-producing Enterobacteriaceae in Hong Kong
T2 - transition from epidemic to endemic setting
AU - Wong, Shuk Ching
AU - Chan, Veronica Wing Man
AU - Lam, Germaine Kit Ming
AU - AuYeung, Christine Ho Yan
AU - Leung, Elaine Yin Ling
AU - So, Simon Yung Chun
AU - Chen, Jonathan Hon Kwan
AU - Sridhar, Siddharth
AU - Tam, Anthony Raymond
AU - Hung, Ivan Fan Ngai
AU - Ho, Pak Leung
AU - Yuen, Kwok Yung
AU - Cheng, Vincent Chi Chung
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.
PY - 2021/9
Y1 - 2021/9
N2 - A multi-pronged carbapenemase-producing Enterobacteriaceae (CPE) screening strategy was implemented in Hong Kong West healthcare network. Of 199,192 fecal specimens from 77,194 patients screening from 1 July 2011 to 30 June 2019, the incidence of CPE per 1000 patient admission significantly increased from 0.01 (2012) to 1.9 (2018) (p<0.01). With appropriate infection control measures, the incidence of nosocomial CPE per 1000 CPE colonization day decreased from 22.34 (2014) to 10.65 (2018) (p=0.0094). Exposure to wet market for purchasing raw pork (p=0.007), beef (p=0.017), chicken (p=0.026), and vegetable (p=0.034) for >3 times per week significantly associated with community acquisition of CPE. Strategic CPE control measures should be implemented in both the hospital and the community.
AB - A multi-pronged carbapenemase-producing Enterobacteriaceae (CPE) screening strategy was implemented in Hong Kong West healthcare network. Of 199,192 fecal specimens from 77,194 patients screening from 1 July 2011 to 30 June 2019, the incidence of CPE per 1000 patient admission significantly increased from 0.01 (2012) to 1.9 (2018) (p<0.01). With appropriate infection control measures, the incidence of nosocomial CPE per 1000 CPE colonization day decreased from 22.34 (2014) to 10.65 (2018) (p=0.0094). Exposure to wet market for purchasing raw pork (p=0.007), beef (p=0.017), chicken (p=0.026), and vegetable (p=0.034) for >3 times per week significantly associated with community acquisition of CPE. Strategic CPE control measures should be implemented in both the hospital and the community.
KW - Carbapenemase-producing Enterobacteriaceae
KW - Endemicity
KW - Gastrointestinal colonization
UR - http://www.scopus.com/inward/record.url?scp=85102193110&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85102193110&partnerID=8YFLogxK
U2 - 10.1007/s10096-021-04173-x
DO - 10.1007/s10096-021-04173-x
M3 - Article
C2 - 33666789
AN - SCOPUS:85102193110
SN - 0934-9723
VL - 40
SP - 2017
EP - 2022
JO - European Journal of Clinical Microbiology and Infectious Diseases
JF - European Journal of Clinical Microbiology and Infectious Diseases
IS - 9
ER -