Speechless after bone marrow transplantation: A rare complication of parainfluenza virus related group in an adult

W. Y. Au, T. Y. Tsang, A. K.W. Lie, K. Y. Yuen, C. G.C. Oo, R. Liang, Y. L. Kwong

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Upper respiratory tract (URT) viral infections may cause severe consequences during myeloablative bone marrow transplantation (BMT). We present a patient with parainfluenza virus (PIV) infection during the course of BMT. He remained relatively asymptomatic during the course of cytopenia, but presented with complete loss of voice and severe laryngitis a few days after engraftment, which is not usual for adult PIV infections. Seroconversion to PIV and marked increase in antibody titres was demonstrated, with complete lymphoid engraftment. Our case illustrated that the virulence of some URT viral infections depend on host immune factors, and may remain latent until graft versus host responses can be mounted.

Original languageEnglish
Pages (from-to)421-422
Number of pages2
JournalLeukemia and Lymphoma
Volume43
Issue number2
DOIs
Publication statusPublished - 2002
Externally publishedYes

ASJC Scopus Subject Areas

  • Hematology
  • Oncology
  • Cancer Research

Keywords

  • BMT
  • Croup
  • Immuno-reconstitution
  • Parainfluenza virus

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