Solving the mystery of H7N9 by crystal balls

Kwok Yung Yuen

doi:10.1038/cr.2013.150

Solving the mystery of H7N9 by crystal balls

Kwok Yung Yuen

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

How the novel influenza H7N9 virus crossed species barrier from avian to human is intriguing. Extrapolation from previous studies on H5N1 can be misleading as illustrated by crystallographic studies on the H7 hemagglutinin with G226L substitution; crystal structure of the neuraminidase N9 showed that R294K substitution interferes with binding to sialic acid or antiviral drugs and reduces viral fitness.

Original language	English
Pages (from-to)	1335-1336
Number of pages	2
Journal	Cell Research
Volume	23
Issue number	12
DOIs	https://doi.org/10.1038/cr.2013.150
Publication status	Published - Dec 2013
Externally published	Yes

ASJC Scopus Subject Areas

Molecular Biology
Cell Biology

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10.1038/cr.2013.150

Cite this

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Solving the mystery of H7N9 by crystal balls

Abstract

ASJC Scopus Subject Areas

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