Serum Antibody Profile of a Patient with Coronavirus Disease 2019 Reinfection

Kelvin Kai Wang To; Ivan Fan Ngai Hung; Kwok Hung Chan; Shuofeng Yuan; Wing Kin To; Dominic Ngai Chong Tsang; Vincent Chi Chung Cheng; Zhiwei Chen; Kin Hang Kok; Kwok Yung Yuen

doi:10.1093/cid/ciaa1368

Serum Antibody Profile of a Patient with Coronavirus Disease 2019 Reinfection

Kelvin Kai Wang To, Ivan Fan Ngai Hung, Kwok Hung Chan, Shuofeng Yuan, Wing Kin To, Dominic Ngai Chong Tsang, Vincent Chi Chung Cheng, Zhiwei Chen, Kin Hang Kok, Kwok Yung Yuen

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

We recently reported a patient with coronavirus disease 2019 reinfection. Here, we show that serum neutralizing antibodies could be detected during the first episode but not at the presentation of the second episode. During reinfection, neutralizing antibodies and high avidity immunoglobulin G were found within 8 days after hospitalization, whereas immunoglobulin M response was absent.

Original language	English
Pages (from-to)	E659-E662
Journal	Clinical Infectious Diseases
Volume	72
Issue number	10
DOIs	https://doi.org/10.1093/cid/ciaa1368
Publication status	Published - May 15 2021
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2020

ASJC Scopus Subject Areas

Microbiology (medical)
Infectious Diseases

Keywords

Antibody
COVID-19
Immunity
Reinfection
SARS-CoV-2

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10.1093/cid/ciaa1368

Cite this

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title = "Serum Antibody Profile of a Patient with Coronavirus Disease 2019 Reinfection",

abstract = "We recently reported a patient with coronavirus disease 2019 reinfection. Here, we show that serum neutralizing antibodies could be detected during the first episode but not at the presentation of the second episode. During reinfection, neutralizing antibodies and high avidity immunoglobulin G were found within 8 days after hospitalization, whereas immunoglobulin M response was absent.",

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AU - To, Kelvin Kai Wang

AU - Hung, Ivan Fan Ngai

AU - Chan, Kwok Hung

AU - Yuan, Shuofeng

AU - To, Wing Kin

AU - Tsang, Dominic Ngai Chong

AU - Cheng, Vincent Chi Chung

AU - Chen, Zhiwei

AU - Kok, Kin Hang

AU - Yuen, Kwok Yung

PY - 2021/5/15

Y1 - 2021/5/15

N2 - We recently reported a patient with coronavirus disease 2019 reinfection. Here, we show that serum neutralizing antibodies could be detected during the first episode but not at the presentation of the second episode. During reinfection, neutralizing antibodies and high avidity immunoglobulin G were found within 8 days after hospitalization, whereas immunoglobulin M response was absent.

AB - We recently reported a patient with coronavirus disease 2019 reinfection. Here, we show that serum neutralizing antibodies could be detected during the first episode but not at the presentation of the second episode. During reinfection, neutralizing antibodies and high avidity immunoglobulin G were found within 8 days after hospitalization, whereas immunoglobulin M response was absent.

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KW - Immunity

KW - Reinfection

KW - SARS-CoV-2

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JF - Clinical Infectious Diseases

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Serum Antibody Profile of a Patient with Coronavirus Disease 2019 Reinfection

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Access to Document

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