Oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus, Hong Kong, China

Honglin Chen; Chung Lam Cheung; Hung Tai; Pengxi Zhao; Jasper F.W. Chan; Vincent C.C. Cheng; Kwok Hung Chan; Kwok Yung Yuen

doi:10.3201/eid1512.091057

Oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus, Hong Kong, China

Honglin Chen, Chung Lam Cheung, Hung Tai, Pengxi Zhao, Jasper F.W. Chan, Vincent C.C. Cheng, Kwok Hung Chan, Kwok Yung Yuen

Research output: Contribution to journal › Article › peer-review

96 Citations (Scopus)

Abstract

Resistance to oseltamivir was observed in influenza A pandemic (H1N1) 2009 virus isolated from an untreated person in Hong Kong, China. Investigations showed a resistant virus with the neuraminidase (NA) 274Y genotype in quasi-species from a nasopharyngeal aspirate. Monitoring for the naturally occurring NA 274Y mutation in this virus is necessary.

Original language	English
Pages (from-to)	1970-1972
Number of pages	3
Journal	Emerging Infectious Diseases
Volume	15
Issue number	12
DOIs	https://doi.org/10.3201/eid1512.091057
Publication status	Published - Dec 2009
Externally published	Yes

ASJC Scopus Subject Areas

Epidemiology
Microbiology (medical)
Infectious Diseases

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10.3201/eid1512.091057

Cite this

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abstract = "Resistance to oseltamivir was observed in influenza A pandemic (H1N1) 2009 virus isolated from an untreated person in Hong Kong, China. Investigations showed a resistant virus with the neuraminidase (NA) 274Y genotype in quasi-species from a nasopharyngeal aspirate. Monitoring for the naturally occurring NA 274Y mutation in this virus is necessary.",

author = "Honglin Chen and Cheung, {Chung Lam} and Hung Tai and Pengxi Zhao and Chan, {Jasper F.W.} and Cheng, {Vincent C.C.} and Chan, {Kwok Hung} and Yuen, {Kwok Yung}",

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AU - Chen, Honglin

AU - Cheung, Chung Lam

AU - Tai, Hung

AU - Zhao, Pengxi

AU - Chan, Jasper F.W.

AU - Cheng, Vincent C.C.

AU - Chan, Kwok Hung

AU - Yuen, Kwok Yung

PY - 2009/12

Y1 - 2009/12

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AB - Resistance to oseltamivir was observed in influenza A pandemic (H1N1) 2009 virus isolated from an untreated person in Hong Kong, China. Investigations showed a resistant virus with the neuraminidase (NA) 274Y genotype in quasi-species from a nasopharyngeal aspirate. Monitoring for the naturally occurring NA 274Y mutation in this virus is necessary.

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Oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus, Hong Kong, China

Abstract

ASJC Scopus Subject Areas

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