Immunorestitution diseases in patients not infected with HIV

V. C.C. Cheng; K. Y. Yuen; S. S.Y. Wong; P. C.Y. Woo; P. L. Ho; R. Lee; R. M.T. Chan

doi:10.1007/s100960100507

Immunorestitution diseases in patients not infected with HIV

V. C.C. Cheng, K. Y. Yuen, S. S.Y. Wong, P. C.Y. Woo, P. L. Ho, R. Lee, R. M.T. Chan

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Abstract

The aim of this study was to assess the clinical spectrum of immunorestitution disease (IRD) in hospitalized patients over a 12-month period. In nine of 18 patients who presented with clinical deterioration during reduction or cessation of immunosuppressants (n = 6) or bone marrow engraftment (n = 3), IRD cases included the following infections: scabies infestation (n = 1); gastric strongyloidiasis (n = 1); hepatosplenic candidiasis (n = 1); methicillin-resistant Staphylococcus aureus abscess formation (n = 2); polyomavirus-related hemorrhagic cystitis (n = 3); and influenza A pneumonitis (n = 1). Immunopathological damage during withdrawal of immunosuppression is an incidental way to uncover an asymptomatic infectious disease. Serial monitoring of hematological and clinical profiles is essential in making a diagnosis of IRD.

Original language	English
Pages (from-to)	402-406
Number of pages	5
Journal	European Journal of Clinical Microbiology and Infectious Diseases
Volume	20
Issue number	6
DOIs	https://doi.org/10.1007/s100960100507
Publication status	Published - 2001
Externally published	Yes

ASJC Scopus Subject Areas

Microbiology (medical)
Infectious Diseases

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10.1007/s100960100507

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abstract = "The aim of this study was to assess the clinical spectrum of immunorestitution disease (IRD) in hospitalized patients over a 12-month period. In nine of 18 patients who presented with clinical deterioration during reduction or cessation of immunosuppressants (n = 6) or bone marrow engraftment (n = 3), IRD cases included the following infections: scabies infestation (n = 1); gastric strongyloidiasis (n = 1); hepatosplenic candidiasis (n = 1); methicillin-resistant Staphylococcus aureus abscess formation (n = 2); polyomavirus-related hemorrhagic cystitis (n = 3); and influenza A pneumonitis (n = 1). Immunopathological damage during withdrawal of immunosuppression is an incidental way to uncover an asymptomatic infectious disease. Serial monitoring of hematological and clinical profiles is essential in making a diagnosis of IRD.",

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AU - Cheng, V. C.C.

AU - Yuen, K. Y.

AU - Wong, S. S.Y.

AU - Woo, P. C.Y.

AU - Ho, P. L.

AU - Lee, R.

AU - Chan, R. M.T.

PY - 2001

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AB - The aim of this study was to assess the clinical spectrum of immunorestitution disease (IRD) in hospitalized patients over a 12-month period. In nine of 18 patients who presented with clinical deterioration during reduction or cessation of immunosuppressants (n = 6) or bone marrow engraftment (n = 3), IRD cases included the following infections: scabies infestation (n = 1); gastric strongyloidiasis (n = 1); hepatosplenic candidiasis (n = 1); methicillin-resistant Staphylococcus aureus abscess formation (n = 2); polyomavirus-related hemorrhagic cystitis (n = 3); and influenza A pneumonitis (n = 1). Immunopathological damage during withdrawal of immunosuppression is an incidental way to uncover an asymptomatic infectious disease. Serial monitoring of hematological and clinical profiles is essential in making a diagnosis of IRD.

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Immunorestitution diseases in patients not infected with HIV

Abstract

ASJC Scopus Subject Areas

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