Immunogenicity, safety and tolerability of intradermal influenza vaccines

Ivan F.N. Hung, Kwok Yung Yuen

Research output: Contribution to journalReview articlepeer-review

23 Citations (Scopus)

Abstract

Intradermal influenza vaccination has been studied for more than 80 y. The revived interest in this strategy of vaccination is a result of the innovative technologies in needle design allowing more precise injection and making the device easier to use. Furthermore, clinical trials on these novel devices have demonstrated significant dose sparing effects, improved immunogenicity and very few adverse effects. This review compares intradermal vaccination with various devices with subcutaneous and intramuscular vaccination. We also discussed the role of topical adjuvant before intradermal vaccination.

Original languageEnglish
Pages (from-to)565-570
Number of pages6
JournalHuman Vaccines and Immunotherapeutics
Volume14
Issue number3
DOIs
Publication statusPublished - Mar 4 2018
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2018 Taylor & Francis.

ASJC Scopus Subject Areas

  • Immunology and Allergy
  • Immunology
  • Pharmacology

Keywords

  • adjuvant
  • influenza
  • intradermal
  • vaccination

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