Human metapneumovirus infection in an immunocompetent adult presenting as mononucleosis-like illness

Iris W.S. Li; Kelvin K.W. To; Bone S.F. Tang; Kwok Hung Chan; Chee Kin Hui; Vincent C.C. Cheng; Kwok Yung Yuen

doi:10.1016/j.jinf.2008.03.005

Human metapneumovirus infection in an immunocompetent adult presenting as mononucleosis-like illness

Iris W.S. Li, Kelvin K.W. To, Bone S.F. Tang, Kwok Hung Chan, Chee Kin Hui, Vincent C.C. Cheng, Kwok Yung Yuen

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

A 37-year-old man was presented with incidental findings of neutropenia, atypical lymphocytosis, thrombocytopenia and deranged liver parenchymal enzymes. Four days later, he developed fever, sore throat and cervical lymphadenopathy, compatible with mononucleosis-like illness (MLI). Polymerase chain reaction (PCR) and viral culture of the nasopharyngeal swab showed human metapneumovirus (hMPV). There was a ≥4-fold rise in IgG against hMPV. This is the first case report illustrating the natural clinical course of hMPV-related MLI.

Original language	English
Pages (from-to)	389-392
Number of pages	4
Journal	Journal of Infection
Volume	56
Issue number	5
DOIs	https://doi.org/10.1016/j.jinf.2008.03.005
Publication status	Published - May 2008
Externally published	Yes

ASJC Scopus Subject Areas

Microbiology (medical)
Infectious Diseases

Keywords

Human metapneumovirus
Infectious mononucleosis
Mononucleosis-like illness

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10.1016/j.jinf.2008.03.005

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title = "Human metapneumovirus infection in an immunocompetent adult presenting as mononucleosis-like illness",

abstract = "A 37-year-old man was presented with incidental findings of neutropenia, atypical lymphocytosis, thrombocytopenia and deranged liver parenchymal enzymes. Four days later, he developed fever, sore throat and cervical lymphadenopathy, compatible with mononucleosis-like illness (MLI). Polymerase chain reaction (PCR) and viral culture of the nasopharyngeal swab showed human metapneumovirus (hMPV). There was a ≥4-fold rise in IgG against hMPV. This is the first case report illustrating the natural clinical course of hMPV-related MLI.",

keywords = "Human metapneumovirus, Infectious mononucleosis, Mononucleosis-like illness",

author = "Li, {Iris W.S.} and To, {Kelvin K.W.} and Tang, {Bone S.F.} and Chan, {Kwok Hung} and Hui, {Chee Kin} and Cheng, {Vincent C.C.} and Yuen, {Kwok Yung}",

year = "2008",

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doi = "10.1016/j.jinf.2008.03.005",

language = "English",

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pages = "389--392",

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TY - JOUR

T1 - Human metapneumovirus infection in an immunocompetent adult presenting as mononucleosis-like illness

AU - Li, Iris W.S.

AU - To, Kelvin K.W.

AU - Tang, Bone S.F.

AU - Chan, Kwok Hung

AU - Hui, Chee Kin

AU - Cheng, Vincent C.C.

AU - Yuen, Kwok Yung

PY - 2008/5

Y1 - 2008/5

N2 - A 37-year-old man was presented with incidental findings of neutropenia, atypical lymphocytosis, thrombocytopenia and deranged liver parenchymal enzymes. Four days later, he developed fever, sore throat and cervical lymphadenopathy, compatible with mononucleosis-like illness (MLI). Polymerase chain reaction (PCR) and viral culture of the nasopharyngeal swab showed human metapneumovirus (hMPV). There was a ≥4-fold rise in IgG against hMPV. This is the first case report illustrating the natural clinical course of hMPV-related MLI.

AB - A 37-year-old man was presented with incidental findings of neutropenia, atypical lymphocytosis, thrombocytopenia and deranged liver parenchymal enzymes. Four days later, he developed fever, sore throat and cervical lymphadenopathy, compatible with mononucleosis-like illness (MLI). Polymerase chain reaction (PCR) and viral culture of the nasopharyngeal swab showed human metapneumovirus (hMPV). There was a ≥4-fold rise in IgG against hMPV. This is the first case report illustrating the natural clinical course of hMPV-related MLI.

KW - Human metapneumovirus

KW - Infectious mononucleosis

KW - Mononucleosis-like illness

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VL - 56

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JO - Journal of Infection

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ER -

Human metapneumovirus infection in an immunocompetent adult presenting as mononucleosis-like illness

Abstract

ASJC Scopus Subject Areas

Keywords

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