False-negative cerebrospinal fluid cryptococcal antigen test due to small-colony variants of Cryptococcus neoformans meningitis in a patient with cystopleural shunt

Kelvin K.W. To; Vincent C.C. Cheng; Bone S.F. Tang; Yiu Wah Fan; Kwok Yung Yuen

doi:10.1080/00365540600664118

False-negative cerebrospinal fluid cryptococcal antigen test due to small-colony variants of Cryptococcus neoformans meningitis in a patient with cystopleural shunt

Kelvin K.W. To, Vincent C.C. Cheng, Bone S.F. Tang, Yiu Wah Fan, Kwok Yung Yuen

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

This is the first report of a small-colony variant Cryptococcus neoformans isolated from the cerebrospinal fluid of a patient with cystopleural shunt associated chronic meningitis. Cryptococcal antigen testing of the cerebrospinal fluid and the serum were both negative. The atypical morphology and the false-negative test may lead to delay of diagnosis and treatment.

Original language	English
Pages (from-to)	1110-1114
Number of pages	5
Journal	Scandinavian Journal of Infectious Diseases
Volume	38
Issue number	11-12
DOIs	https://doi.org/10.1080/00365540600664118
Publication status	Published - Nov 2006
Externally published	Yes

ASJC Scopus Subject Areas

General Immunology and Microbiology
Microbiology (medical)
Infectious Diseases

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10.1080/00365540600664118

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False-negative cerebrospinal fluid cryptococcal antigen test due to small-colony variants of Cryptococcus neoformans meningitis in a patient with cystopleural shunt. / To, Kelvin K.W.; Cheng, Vincent C.C.; Tang, Bone S.F. et al.
In: Scandinavian Journal of Infectious Diseases, Vol. 38, No. 11-12, 11.2006, p. 1110-1114.

Research output: Contribution to journal › Article › peer-review

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abstract = "This is the first report of a small-colony variant Cryptococcus neoformans isolated from the cerebrospinal fluid of a patient with cystopleural shunt associated chronic meningitis. Cryptococcal antigen testing of the cerebrospinal fluid and the serum were both negative. The atypical morphology and the false-negative test may lead to delay of diagnosis and treatment.",

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AB - This is the first report of a small-colony variant Cryptococcus neoformans isolated from the cerebrospinal fluid of a patient with cystopleural shunt associated chronic meningitis. Cryptococcal antigen testing of the cerebrospinal fluid and the serum were both negative. The atypical morphology and the false-negative test may lead to delay of diagnosis and treatment.

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False-negative cerebrospinal fluid cryptococcal antigen test due to small-colony variants of Cryptococcus neoformans meningitis in a patient with cystopleural shunt

Abstract

ASJC Scopus Subject Areas

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