Disseminated infections with talaromyces marneffei in non-AIDS patients given monoclonal antibodies against CD20 and kinase inhibitors

Jasper F.W. Chan; Thomas S.Y. Chan; Harinder Gill; Frank Y.F. Lam; Nigel J. Trendell-Smith; Siddharth Sridhar; Herman Tse; Susanna K.P. Lau; Ivan F.N. Hung; Kwok Yung Yuen; Patrick C.Y. Woo

doi:10.3201/eid2107.150138

Disseminated infections with talaromyces marneffei in non-AIDS patients given monoclonal antibodies against CD20 and kinase inhibitors

Jasper F.W. Chan, Thomas S.Y. Chan, Harinder Gill, Frank Y.F. Lam, Nigel J. Trendell-Smith, Siddharth Sridhar, Herman Tse, Susanna K.P. Lau, Ivan F.N. Hung, Kwok Yung Yuen, Patrick C.Y. Woo

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69 Citations (Scopus)

Abstract

Infections with the fungus Talaromyces (formerly Penicillium) marneffei are rare in patients who do not have AIDS. We report disseminated T. marneffei infection in 4 hematology patients without AIDS who received targeted therapy with monoclonal antibodies against CD20 or kinase inhibitors during the past 2 years. Clinicians should be aware of this emerging complication, especially in patients from disease-endemic regions.

Original language	English
Pages (from-to)	1101-1106
Number of pages	6
Journal	Emerging Infectious Diseases
Volume	21
Issue number	7
DOIs	https://doi.org/10.3201/eid2107.150138
Publication status	Published - 2015
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2015, Centers for Disease Control and Prevention (CDC). All rights reserved.

ASJC Scopus Subject Areas

Epidemiology
Microbiology (medical)
Infectious Diseases

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10.3201/eid2107.150138

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Chan, J. F. W., Chan, T. S. Y., Gill, H., Lam, F. Y. F., Trendell-Smith, N. J., Sridhar, S., Tse, H., Lau, S. K. P., Hung, I. F. N., Yuen, K. Y., & Woo, P. C. Y. (2015). Disseminated infections with talaromyces marneffei in non-AIDS patients given monoclonal antibodies against CD20 and kinase inhibitors. Emerging Infectious Diseases, 21(7), 1101-1106. https://doi.org/10.3201/eid2107.150138

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abstract = "Infections with the fungus Talaromyces (formerly Penicillium) marneffei are rare in patients who do not have AIDS. We report disseminated T. marneffei infection in 4 hematology patients without AIDS who received targeted therapy with monoclonal antibodies against CD20 or kinase inhibitors during the past 2 years. Clinicians should be aware of this emerging complication, especially in patients from disease-endemic regions.",

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AU - Gill, Harinder

AU - Lam, Frank Y.F.

AU - Trendell-Smith, Nigel J.

AU - Sridhar, Siddharth

AU - Tse, Herman

AU - Lau, Susanna K.P.

AU - Hung, Ivan F.N.

AU - Yuen, Kwok Yung

AU - Woo, Patrick C.Y.

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Disseminated infections with talaromyces marneffei in non-AIDS patients given monoclonal antibodies against CD20 and kinase inhibitors

Abstract

Bibliographical note

ASJC Scopus Subject Areas

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