Clinical and molecular epidemiology of human parainfluenza virus 4 infections in Hong Kong: Subtype 4B as common as subtype 4A

Susanna K.P. Lau; Kenneth S.M. Li; Kam Yu Chau; Lok Yee So; Rodney A. Lee; Yu Lung Lau; Kwok Hung Chan; Wilina W.L. Lim; Patrick C.Y. Woo; Kwok Yung Yuen

doi:10.1128/JCM.00047-09

Clinical and molecular epidemiology of human parainfluenza virus 4 infections in Hong Kong: Subtype 4B as common as subtype 4A

Susanna K.P. Lau, Kenneth S.M. Li, Kam Yu Chau, Lok Yee So, Rodney A. Lee, Yu Lung Lau, Kwok Hung Chan, Wilina W.L. Lim, Patrick C.Y. Woo, Kwok Yung Yuen

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Abstract

In this 1-year study, 35 (1.2%) of 2,912 nasopharyngeal aspirates were positive for human parainfluenza virus 4 (HPIV4) by reverse transcription-PCR. Patients with HPIV4 infection were mainly young children and immunocompromised adults. In contrast to the reported predominance of HPIV4A infection, molecular subtyping revealed that 15 (44%) cases were caused by HPIV4B.

Original language	English
Pages (from-to)	1549-1552
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	47
Issue number	5
DOIs	https://doi.org/10.1128/JCM.00047-09
Publication status	Published - May 2009
Externally published	Yes

ASJC Scopus Subject Areas

Microbiology (medical)

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title = "Clinical and molecular epidemiology of human parainfluenza virus 4 infections in Hong Kong: Subtype 4B as common as subtype 4A",

abstract = "In this 1-year study, 35 (1.2%) of 2,912 nasopharyngeal aspirates were positive for human parainfluenza virus 4 (HPIV4) by reverse transcription-PCR. Patients with HPIV4 infection were mainly young children and immunocompromised adults. In contrast to the reported predominance of HPIV4A infection, molecular subtyping revealed that 15 (44%) cases were caused by HPIV4B.",

author = "Lau, {Susanna K.P.} and Li, {Kenneth S.M.} and Chau, {Kam Yu} and So, {Lok Yee} and Lee, {Rodney A.} and Lau, {Yu Lung} and Chan, {Kwok Hung} and Lim, {Wilina W.L.} and Woo, {Patrick C.Y.} and Yuen, {Kwok Yung}",

year = "2009",

month = may,

doi = "10.1128/JCM.00047-09",

language = "English",

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pages = "1549--1552",

journal = "Journal of Clinical Microbiology",

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T1 - Clinical and molecular epidemiology of human parainfluenza virus 4 infections in Hong Kong

T2 - Subtype 4B as common as subtype 4A

AU - Lau, Susanna K.P.

AU - Li, Kenneth S.M.

AU - Chau, Kam Yu

AU - So, Lok Yee

AU - Lee, Rodney A.

AU - Lau, Yu Lung

AU - Chan, Kwok Hung

AU - Lim, Wilina W.L.

AU - Woo, Patrick C.Y.

AU - Yuen, Kwok Yung

PY - 2009/5

Y1 - 2009/5

N2 - In this 1-year study, 35 (1.2%) of 2,912 nasopharyngeal aspirates were positive for human parainfluenza virus 4 (HPIV4) by reverse transcription-PCR. Patients with HPIV4 infection were mainly young children and immunocompromised adults. In contrast to the reported predominance of HPIV4A infection, molecular subtyping revealed that 15 (44%) cases were caused by HPIV4B.

AB - In this 1-year study, 35 (1.2%) of 2,912 nasopharyngeal aspirates were positive for human parainfluenza virus 4 (HPIV4) by reverse transcription-PCR. Patients with HPIV4 infection were mainly young children and immunocompromised adults. In contrast to the reported predominance of HPIV4A infection, molecular subtyping revealed that 15 (44%) cases were caused by HPIV4B.

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Clinical and molecular epidemiology of human parainfluenza virus 4 infections in Hong Kong: Subtype 4B as common as subtype 4A

Abstract

ASJC Scopus Subject Areas

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