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Talaromyces marneffei Mp1p Is a Virulence Factor that Binds and Sequesters a Key Proinflammatory Lipid to Dampen Host Innate Immune Response
Sze, K. H., Lam, W. H., Zhang, H., Ke, Y. H., Tse, M. K., Woo, P. C. Y., Lau, S. K. P., Lau, C. C. Y., Cai, J. P., Tung, E. T. K., Lo, R. K. C., Xu, S., Kao, R. Y. T., Hao, Q. & Yuen, K. Y., Feb 16 2017, In: Cell Chemical Biology. 24, 2, p. 182-194 13 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Citations (Scopus) -
Talaromyces marneffei Mp1 protein, a novel virulence factor, carries two arachidonic acid-binding domains to suppress inflammatory responses in hosts
Lam, W. H., Sze, K. H., Ke, Y., Tse, M. K., Zhang, H., Woo, P. C. Y., Lau, S. K. P., Lau, C. C. Y., Xu, S., Lai, P. M., Zhou, T., Kao, R. Y. T., Yuen, K. Y., Hao, Q. & Antonyuk, S. V., Apr 1 2019, In: Infection and Immunity. 87, 4, e00679.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus) -
Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity
Chu, H., Shuai, H., Hou, Y., Zhang, X., Wen, L., Huang, X., Hu, B., Yang, D., Wang, Y., Yoon, C., Wong, B. H. Y., Li, C., Zhao, X., Poon, V. K. M., Cai, J. P., Wong, K. K. Y., Yeung, M. L., Zhou, J., Au-Yeung, R. K. H. & Yuan, S. & 5 others, , Jun 2021, In: Science advances. 7, 25, abf8577.Research output: Contribution to journal › Article › peer-review
Open Access66 Citations (Scopus) -
Targeting papain-like protease for broad-spectrum coronavirus inhibition
Yuan, S., Gao, X., Tang, K., Cai, J. P., Hu, M., Luo, P., Wen, L., Ye, Z. W., Luo, C., Tsang, J. O. L., Chan, C. C. Y., Huang, Y., Cao, J., Liang, R., Qin, Z., Qin, B., Yin, F., Chu, H., Jin, D. Y. & Sun, R. & 3 others, , Dec 2022, In: Protein and Cell. 13, 12, p. 940-953 14 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Citations (Scopus) -
Targeting SUMO modification of the non-structural protein 5 of zika virus as a host-targeting antiviral strategy
Zhu, Z., Chu, H., Wen, L., Yuan, S., Chik, K. K. H., Yuen, T. T. T., Yip, C. C. Y., Wang, D., Zhou, J., Yin, F., Jin, D. Y., Kok, K. H., Yuen, K. Y. & Chan, J. F. W., Jan 2 2019, In: International Journal of Molecular Sciences. 20, 2, 392.Research output: Contribution to journal › Article › peer-review
Open Access21 Citations (Scopus) -
Targeting the Inositol-Requiring Enzyme-1 Pathway Efficiently Reverts Zika Virus-Induced Neurogenesis and Spermatogenesis Marker Perturbations
Chu, H., Yuen, T. T. T., Chik, K. K. H., Yuan, S., Shuai, H., Zou, Z., Wang, Y., Zhu, Z., Yang, D., Poon, V. K. M., Chan, C. C. S., Zhou, J., Yin, F., Kok, K. H., Yuen, K. Y. & Chan, J. F. W., Jul 10 2020, In: ACS Infectious Diseases. 6, 7, p. 1745-1758 14 p.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus) -
Taxonomy of the order Mononegavirales: update 2016
Afonso, C. L., Amarasinghe, G. K., Bányai, K., Bào, Y., Basler, C. F., Bavari, S., Bejerman, N., Blasdell, K. R., Briand, F. X., Briese, T., Bukreyev, A., Calisher, C. H., Chandran, K., Chéng, J., Clawson, A. N., Collins, P. L., Dietzgen, R. G., Dolnik, O., Domier, L. L. & Dürrwald, R. & 63 others, , Aug 1 2016, In: Archives of Virology. 161, 8, p. 2351-2360 10 p.Research output: Contribution to journal › Article › peer-review
Open Access397 Citations (Scopus) -
Television viewing time in Hong Kong adult population: Associations with body mass index and obesity
Xie, Y. J., Stewart, S. M., Lam, T. H., Viswanath, K. & Chan, S. S., Jan 10 2014, In: PLoS ONE. 9, 1, e85440.Research output: Contribution to journal › Article › peer-review
Open Access35 Citations (Scopus) -
Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study
To, K. K. W., Tsang, O. T. Y., Leung, W. S., Tam, A. R., Wu, T. C., Lung, D. C., Yip, C. C. Y., Cai, J. P., Chan, J. M. C., Chik, T. S. H., Lau, D. P. L., Choi, C. Y. C., Chen, L. L., Chan, W. M., Chan, K. H., Ip, J. D., Ng, A. C. K., Poon, R. W. S., Luo, C. T. & Cheng, V. C. C. & 5 others, , May 2020, In: The Lancet Infectious Diseases. 20, 5, p. 565-574 10 p.Research output: Contribution to journal › Article › peer-review
Open Access2443 Citations (Scopus) -
Ten-year experience with liver transplantation at Queen Mary Hospital: retrospective study.
Lo, C. M., Fan, S. T., Liu, C. L., Yong, B. H., Lai, C. L., Lau, G. K., Wei, W. I., Tam, P. K., Tsoi, N. S., Ng, I. O., Young, K., Chan, J. K., Tso, W. K., Yuen, K. Y. & Wong, J., Aug 2002, In: Hong Kong Medical Journal. 8, 4, p. 240-244 5 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
Test–retest reliability and validity of a single-item Self-reported Family Happiness Scale in Hong Kong Chinese: findings from Hong Kong Jockey Club FAMILY Project
Shen, C., Wang, M. P., Ho, H. C. Y., Wan, A., Stewart, S. M., Viswanath, K., Chan, S. S. C. & Lam, T. H., Feb 15 2019, In: Quality of Life Research. 28, 2, p. 535-543 9 p.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus) -
Test-retest reliability of a computer-assisted self-administered questionnaire on early life exposure in a nasopharyngeal carcinoma case-control study
Mai, Z. M., Lin, J. H., Chiang, S. C., Ngan, R. K. C., Kwong, D. L. W., Ng, W. T., Ng, A. W. Y., Yuen, K. T., Ip, K. M., Chan, Y. H., Lee, A. W. M., Ho, S. Y., Lung, M. L. & Lam, T. H., Dec 1 2018, In: Scientific Reports. 8, 1, 7052.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
The 2008-2009 H1N1 influenza virus exhibits reduced susceptibility to antibody inhibition: Implications for the prevalence of oseltamivir resistant variant viruses
Wu, W. L., Lau, S. Y., Chen, Y., Wang, G., Mok, B. W. Y., Wen, X., Wang, P., Song, W., Lin, T., Chan, K. H., Yuen, K. Y. & Chen, H., Jan 2012, In: Antiviral Research. 93, 1, p. 144-153 10 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Citations (Scopus) -
The alcohol industry lobby and Hong Kongs zero wine and beer tax policy
Yoon, S. & Lam, T. H., 2012, In: BMC Public Health. 12, 1, 717.Research output: Contribution to journal › Article › peer-review
Open Access24 Citations (Scopus) -
The Association Between Adolescents' Depressive Symptoms, Maternal Negative Affect, and Family Relationships in Hong Kong: Cross-Sectional and Longitudinal Findings
Leung, S. S. K., Stewart, S. M., Wong, J. P. S., Ho, D. S. Y., Fong, D. Y. T. & Lam, T. H., Oct 2009, In: Journal of Family Psychology. 23, 5, p. 636-645 10 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
The association between depressive symptoms and mortality among Chinese elderly: A Hong Kong cohort study
Sun, W., Schooling, C. M., Chan, W. M., Ho, K. S. & Lam, T. H., Apr 2011, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 66 A, 4, p. 459-466 8 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Citations (Scopus) -
The Association between Electronic Device Use during Family Time and Family Well-Being: Population-Based Cross-Sectional Study
Zhao, S. Z., Guo, N., Wang, M. P., Fong, D. Y. T., Lai, A. Y. K., Chan, S. S. C., Lam, T. H. & Ho, D. S. Y., Oct 2020, In: Journal of Medical Internet Research. 22, 10, e20529.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
The association between resting heart rate, cardiovascular disease and mortality: Evidence from 112,680 men and women in 12 cohorts
Woodward, M., Webster, R., Murakami, Y., Barzi, F., Lam, T. H., Fang, X., Suh, I., Batty, G. D., Huxley, R. & Rodgers, A., Jun 2014, In: European Journal of Preventive Cardiology. 21, 6, p. 719-726 8 p.Research output: Contribution to journal › Article › peer-review
Open Access91 Citations (Scopus) -
The association of problematic smartphone use with family well-being mediated by family communication in Chinese adults: A population-based study
Guo, N., Wang, M. P., Luk, T. T., Ho, S. Y., Fong, D. Y. T., Chan, S. S. C. & Lam, T. H., 2019, In: Journal of Behavioral Addictions. 8, 3, p. 412-419 8 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Citations (SciVal) -
The association of pulmonary function with carotid atherosclerosis in older Chinese: Guangzhou Biobank Cohort Study-CVD Subcohort
Pan, J., Xu, L., Cai, S. X., Jiang, C. Q., Cheng, K. K., Zhao, H. J., Zhang, W. S., Jin, Y. L., Lin, J. M., Thomas, G. N. & Lam, T. H., Dec 1 2015, In: Atherosclerosis. 243, 2, p. 469-476 8 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (Scopus) -
The biosynthetic pathway for a thousand-year-old natural food colorant and citrinin in Penicillium marneffei
Woo, P. C. Y., Lam, C. W., Tam, E. W. T., Lee, K. C., Yung, K. K. Y., Leung, C. K. F., Sze, K. H., Lau, S. K. P. & Yuen, K. Y., Oct 22 2014, In: Scientific Reports. 4, 6728.Research output: Contribution to journal › Article › peer-review
Open Access69 Citations (Scopus) -
The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy
Chan, J. F. W., Zhu, Z., Chu, H., Yuan, S., Chik, K. K. H., Chan, C. C. S., Poon, V. K. M., Yip, C. C. Y., Zhang, X., Tsang, J. O. L., Zou, Z., Tee, K. M., Shuai, H., Lu, G. & Yuen, K. Y., Dec 2018, In: Antiviral Research. 160, p. 38-47 10 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Citations (Scopus) -
The CHADS2 and CHA2DS2-VASc scores predict adverse vascular function, ischemic stroke and cardiovascular death in high-risk patients without atrial fibrillation: Role of incorporating PR prolongation
Chan, Y. H., Yiu, K. H., Lau, K. K., Yiu, Y. F., Li, S. W., Lam, T. H., Lau, C. P., Siu, C. W. & Tse, H. F., Dec 1 2014, In: Atherosclerosis. 237, 2, p. 504-513 10 p.Research output: Contribution to journal › Article › peer-review
56 Citations (Scopus) -
The challenge of patient empowerment in hand hygiene promotion in health care facilities in Hong Kong
Cheng, V. C. C., Wong, S. C., Wong, I. W. Y., Chau, P. H., So, S. Y. C., Wong, S. C. Y., Chen, J. H. K., Lee, W. M., Tai, J. W. M., Chau, C. H., Lo, W. K. & Yuen, K. Y., May 1 2017, In: American Journal of Infection Control. 45, 5, p. 562-565 4 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
The complete genome and proteome of laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats
Woo, P. C. Y., Lau, S. K. P., Tse, H., Teng, J. L. L., Curreem, S. O. T., Tsang, A. K. L., Fan, R. Y. Y., Wong, G. K. M., Huang, Y., Loman, N. J., Snyder, L. A. S., Cai, J. J., Huang, J. D., Mak, W., Pallen, M. J., Lok, S. & Yuen, K. Y., Mar 2009, In: PLoS Genetics. 5, 3Research output: Contribution to journal › Article › peer-review
Open Access53 Citations (Scopus) -
The complete genome sequence of severe acute respiratory syndrome coronavirus strain HKU-39849 (HK-39)
Zeng, F. Y., Chan, C. W. M., Chan, M. N., Chen, J. D., Chow, K. Y. C., Hon, C. C., Hui, K. H., Li, J., Li, V. Y. Y., Wang, C. Y., Wang, P. Y., Guan, Y., Zheng, B., Poon, L. L. M., Chan, K. H., Yuen, K. Y., Peiris, J. S. M. & Leung, F. C., Jul 2003, In: Experimental Biology and Medicine. 228, 7, p. 866-873 8 p.Research output: Contribution to journal › Article › peer-review
Open Access59 Citations (Scopus) -
The correlates of depressed mood in adolescents in Hong Kong
Stewart, S. M., Betson, C. L., Lam, T. H., Chung, S. F., Ho, H. H. & Chung, T. C. F., Jul 1999, In: Journal of Adolescent Health. 25, 1, p. 27-34 8 p.Research output: Contribution to journal › Article › peer-review
47 Citations (Scopus) -
The crystal structure of the emerging human-infecting hepatitis E virus E2s protein
Bai, C., Cai, J., Han, P., Qi, J., Yuen, K. Y. & Wang, Q., Oct 29 2020, In: Biochemical and Biophysical Research Communications. 532, 1, p. 25-31 7 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
The C-Terminal 300 Amino Acid Residues of the G Protein and Putative Open Reading Frame X of the G Gene of Tailam Paramyxovirus (TlmPV) Are Not Required for Replication in Tissue Culture Cells
Kang, H., Zhou, L., Xu, S., Yuen, K. Y., Wah, T. H., Li, Q., Li, G. & He, B., Jan 2023, In: Journal of Virology. 97, 1Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
The development and evaluation of an integrated community-based, patient-centred learning activity at the University of Hong Kong
Leung, G. M., Fielding, R., Chan, M. F., Lee, A., Cheng, Y. H., Yu, C. & Lam, T. H., 2002, In: Medical Education. 36, 10, p. 992-995 4 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
The discrimination of dyslipidaemia using anthropometric measures in ethnically diverse populations of the Asia-pacific region: The obesity in Asia collaboration
Barzi, F., Woodward, M., Czernichow, S., Lee, C. M. Y., Kang, J. H., Janus, E., Lear, S., Patel, A., Caterson, I., Patel, J., Lam, T. H., Suriyawongpaisal, P. & Huxley, R., Feb 2010, In: Obesity Reviews. 11, 2, p. 127-136 10 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
The economic burden of environmental tobacco smoke in the first year of life
Leung, G. M., Ho, L. M. & Lam, T. H., Sept 1 2003, In: Archives of Disease in Childhood. 88, 9, p. 767-771 5 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Citations (Scopus) -
The effectiveness of positive psychology interventions in enhancing positive behaviors and family relationships in Hong Kong: A community-based participatory research project
Zhou, Q., Chan, S. S. C., Stewart, S. M., Leung, C. S. C., Wan, A. & Lam, T. H., Jan 2 2016, In: Journal of Positive Psychology. 11, 1, p. 70-84 15 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
The effectiveness of thoracic manipulation on patients with chronic mechanical neck pain - A randomized controlled trial
Lau, H. M. C., Wing Chiu, T. T. & Lam, T. H., Apr 2011, In: Manual Therapy. 16, 2, p. 141-147 7 p.Research output: Contribution to journal › Article › peer-review
89 Citations (Scopus) -
The effect of alcohol drinking on erectile dysfunction in Chinese men
Lee, A. C. K., Ho, L. M., Yip, A. W. C., Fan, S. & Lam, T. H., Jul 2010, In: International Journal of Impotence Research. 22, 4, p. 272-278 7 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
The effect of a very brief smoking-reduction intervention in smokers who have no intention to quit: Study protocol for a randomized controlled trial Health behavior, health promotion and society
Wu, L., He, Y., Jiang, B., Zhang, D., Tian, H., Zuo, F., Lam, T. H. & Cheung, Y. T. D., Apr 25 2015, In: BMC Public Health. 15, 1, 418.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
The effect of modifiable risk factors on pancreatic cancer mortality in populations of the Asia-Pacific region
Ansary-Moghaddam, A., Huxley, R., Barzi, F., Lawes, C., Ohkubo, T., Fang, X., Jee, S. H., Woodward, M., Okayama, A., Ueshima, H., Maegawa, H., Aoki, N., Nakamura, M., Kubo, N., Yamada, T., Wu, Z. S., Yao, C. H., Andrews, G., Welborn, T. A. & Tang, Z. & 67 others, , Dec 2006, In: Cancer Epidemiology Biomarkers and Prevention. 15, 12, p. 2435-2440 6 p.Research output: Contribution to journal › Article › peer-review
84 Citations (Scopus) -
The effect of physician's 30 s smoking cessation intervention for male medical outpatients: A pilot randomized controlled trial
Lin, P. R., Zhao, Z. W., Cheng, K. K. & Lam, T. H., Sept 2013, In: Journal of Public Health. 35, 3, p. 375-383 9 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (Scopus) -
The Effect of Pseudomonas aeruginosa Infection on Clinical Parameters in Steady-State Bronchiectasis
Ho, P. L., Chan, K. N., Ip, M. S. M., Lam, W. K., Ho, C. S., Yuen, K. Y. & Tsang, K. W. T., 1998, In: Chest. 114, 6, p. 1594-1598 5 p.Research output: Contribution to journal › Article › peer-review
127 Citations (Scopus) -
The effects of air pollution on mortality in socially deprived urban areas in Hong Kong, China
Wong, C. M., Ou, C. Q., Chan, K. P., Chau, Y. K., Thach, T. Q., Yang, L., Chung, R. Y. N., Thomas, G. N., Peiris, J. S. M., Wong, T. W., Hedley, A. J. & Lam, T. H., Sept 2008, In: Environmental Health Perspectives. 116, 9, p. 1189-1194 6 p.Research output: Contribution to journal › Article › peer-review
Open Access119 Citations (Scopus) -
The effects of environmental tobacco smoke on health services utilization in the first eighteen months of life.
Lam, T. H., Leung, G. M. & Ho, L. M., Jun 2001, In: Pediatrics. 107, 6, p. E91Research output: Contribution to journal › Article › peer-review
115 Citations (Scopus) -
The effects of temperature and relative humidity on the viability of the SARS coronavirus
Chan, K. H., Peiris, J. S. M., Lam, S. Y., Poon, L. L. M., Yuen, K. Y. & Seto, W. H., 2011, In: Advances in Virology. 2011, 734690.Research output: Contribution to journal › Article › peer-review
Open Access689 Citations (Scopus) -
The Emergence of Candida auris is Not Associated with Changes in Antifungal Prescription at Hospitals
Wong, S. C., Chau, P. H., Chen, H., So, S. Y. C., Chiu, K. H. Y., Chen, J. H. K., Li, X., Chui, C. S. L., Yuen, K. Y. & Cheng, V. C. C., 2024, In: Infection and Drug Resistance. 17, p. 1419-1429 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The enhancement of infection control in-service education by ward opionion leaders
Seto, W. H., Ching, T. Y., Yuen, K. Y., Chu, Y. B. & Seto, W. L., Apr 1991, In: American Journal of Infection Control. 19, 2, p. 86-91 6 p.Research output: Contribution to journal › Article › peer-review
43 Citations (Scopus) -
The epidemiology and natural history of depressive disorders in Hong Kong's primary care
Chin, W., Lam, C. L. K., Wong, S. Y. S., Lo, Y. Y. C., Fong, D. Y. T., Lam, T., Lee, P. W. H., Wong, J. W. S., Chiu, B. C. F. & Chan, K. T. Y., 2011, In: BMC Family Practice. 12, 129.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
The epidemiology of acinetobacter infections in Hong Kong
Siau, H., Yuen, K. Y., Wong, S. S. Y., Ho, P. L. & Luk, W. K., 1996, In: Journal of Medical Microbiology. 44, 5, p. 340-347 8 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Citations (Scopus) -
The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: An analysis of all 1755 patients
Leung, G. M., Medley, A. J., Ho, L. M., Chau, P., Wong, I. O. L., Thach, T. Q., Ghani, A. C., Donnelly, C. A., Fraser, C., Riley, S., Ferguson, N. M., Anderson, R. M., Tsang, T., Leung, P. Y., Wong, V., Chan, J. C. K., Tsui, E., Lo, S. V. & Lam, T. H., Nov 2 2004, In: Annals of Internal Medicine. 141, 9, p. 662-673 12 p.Research output: Contribution to journal › Article › peer-review
293 Citations (Scopus) -
The epidemiology of stroke amongst women in the Asia - Pacific region
Woodward, M., Tsukinoki-Murakami, R., Murakami, Y., Suh, I., Fang, X., Ueshima, H. & Lam, T. H., May 2011, In: Women's Health. 7, 3, p. 305-317 13 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
The establishment and promotion of the first youth quitline in Hong Kong: Challenges and opportunities
Chan, S. S. C., Wong, D. C. N., Fong, D. Y. T., Leung, A. Y. M., Lam, D. O. B., Mak, Y. W. & Lam, T. H., Sept 2008, In: Evaluation and the Health Professions. 31, 3, p. 258-271 14 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
The first novel influenza A (H1N1) fatality despite antiviral treatment and extracorporeal membrane oxygenation in Hong Kong
Liong, T., Lee, K. L., Poon, Y. S., Lam, S. Y., Chan, C. P., Yue, C. S., Chu, C. M., Yuen, K. Y. & Law, K. I., Oct 2009, In: Hong Kong Medical Journal. 15, 5, p. 381-384 4 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus)